Pulmonary hypertension in obesity-hypoventilation syndrome

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Pulmonary hypertension in hypoventilation syndromes.

In this issue of the European Respiratory Journal, HELD et al. [2] report on 18 patients with severe pulmonary hypertension due to alveolar hypoventilation, who were markedly improved after 3 months of noninvasive bi-level positive-pressure ventilation (NIPPV). Mean pulmonary artery pressure (mPAP) and pulmonary vascular resistance (PVR) were 50 mmHg and 6–7 Wood units, respectively, at baselin...

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We only need to look around us to see that we are in an epidemic of obesity and obesity-related medical problems. The obesity hypoventilation syndrome is a disorder in which an obese person with normal lungs chronically hypoventilates. Obesity impairs ventilatory mechanics, increases the work of breathing and carbon dioxide production, results in respiratory muscle dysfunction, and reduces vent...

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Obesity hypoventilation syndrome.

The term obesity hypoventilation syndrome (OHS) refers to the combination of obesity and chronic hypercapnia that cannot be directly attributed to underlying cardiorespiratory disease. Despite a plethora of potential pathophysiological mechanisms for gas exchange and respiratory control abnormalities that have been described in the obese, the etiology of hypercapnia in OHS has been only partial...

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Defining obesity hypoventilation syndrome.

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ژورنال

عنوان ژورنال: Respiratory Medicine

سال: 2013

ISSN: 0954-6111

DOI: 10.1016/j.rmed.2013.09.017